Summary of Key Facts
Pfizer’s COVID-19 vaccine contains truncated mRNA, which the EMA flagged as a reason for its “major objection,” indicating a preclusion of their approval. Pfizer has not investigated the detrimental outcomes of truncated mRNA in its vaccines. Pfizer submitted Western blot figures to the Food and Drug Administration (FDA) and the EMA that were digitally generated—not from actual experiments. The root cause of such irresponsible conduct by pharma and health authorities is a lack of ethics. When you go to a supermarket and want to buy 10 bottles of whole milk for your children, you usually assume the chemicals and concentrations in these 10 bottles are the same or similar. Most store-bought foods meet our expectations because of regulations and quality control.
What Is Truncated mRNA? Why Does it Matter?
Our DNA contains gene codes composed of nucleotides. DNA makes proteins consisting of amino acids. It consists of a 5′ CAP structure to prime its translation into a spike protein. At the end of the translatable region, the open reading frame, there is a stop codon, which is like a car’s brakes. If a truncated mRNA does not contain a stop codon, it fails to give a “brake” signal. The protein translation process will continue endlessly. It can lead to the production of toxic protein products.
Pfizer’s COVID-19 Vaccine Contains Truncated mRNA
The EMA is responsible for approving all medicinal products for human use in Europe, including drugs and vaccines. The Committee for Medicinal Products for Human Use (CHMP) is the EMA’s committee responsible for interpreting the agency’s opinions. Pfizer mRNA vaccine contains impurities. ( EMA)The EMA demanded that Pfizer provide monthly data on the potential of generating truncated spike proteins/peptides or other proteins/peptides causing autoimmune conditions due to molecular mimicry mechanisms. A deadline was set for July 2021, and an interim report should have been submitted by March 2021.
EMA Flagged Truncated mRNA as a ‘Major Objection’
In an EMA assessment report on “Comirnaty, COVID-19 mRNA vaccine (nucleoside-modified),” coded as EMA/707383/2020, dated Feb. 19, 2021, on page 15 under the section “Manufacturer, process controls and characterisation,” it is stated that “During the procedure, several issues were highlighted relating to the GMP status of the manufacture of the active substance and the testing sites of the finished product for the purpose of batch release. These issues were classified as a Major Objection (MO).”A “major objection” is a formal regulatory red flag by the EMA. If major objections remain unresolved, they preclude granting the marketing authorization. EMA stated a major objection regarding the Pfizer mRNA vaccine. ( EMA)The truncated mRNA has been discussed at length as a “Major Objection” raised by EMA in the two EMA reports we have analyzed above.
Pfizer Recognized Truncated mRNA in Its Vaccines
Pfizer fully recognized the truncated mRNA in its vaccines. Most truncated mRNA is 1,500 to 3,500 nucleotides long with 5’ CAP, missing the Poly(A) tail and the stop codon. They can be translated into a partial spike protein. There are lots of mRNA in the cell. As there is no stop signal, in theory, another mRNA in a cell will take over and continue the unfinished job, prolonging the “spike protein.”If the same spike mRNA takes over, prolonged spike-like proteins with multiple repeats will form. If different mRNA takes over, unknown types of proteins will be created. The annotated graph below is based on a screenshot from page 15 of the EMA report from August 2021. Peak 1 contains the most truncated mRNAs 1,500-3,500 nucleotides long. ( EMA)Strikingly, the precise proportion of impurities of peak 1 was blacked out in this downloaded EMA report.
Pfizer Submitted Digitized Western Blot Figures to FDA and EMA
A “Western blot” method is used to identify specific proteins, allowing researchers to verify the size and abundance of a protein of interest. Because of concerns that incorrect spike protein can cause unexpected injury, the EMA required Pfizer-BioNTech to submit experimental results to demonstrate that truncated COVID-19 vaccine RNA would not produce fragment proteins. However, as this is the first instance of using mRNA as the preventive vaccine for a large population, this is also the first time such a quality issue emerged. The only way to characterize these RNA fragments is by sequencing. One Western blot showed that the truncated mRNA in Peak 1 does not generate proteins in vitro. The annotated figure below is based on a screenshot from page 19 of the EMA report. However, the Western blots are digital or computerized results similar to those presented in December 2020. Fictitious Western blot graph submitted by Pfizer to EMA. (
How Do We Know These Western Blots Are Not Real?
The first step in the Western blotting technique is to separate the proteins in a sample using a molecular biological process called “gel electrophoresis.”As different proteins have different sizes and molecular weights, when they are put in the same electric field, they will run at different speeds from one pole to the other, like a running race. For example, the Western blot graph (below) from the 2021 EMA report appears to be from a real experiment. A common artifact, such as an air bubble between the gel and the blot membrane, probably caused the light spot near the center of Fig. Western blot example from Pfizer’s Covid-19 BNT162b2 experiments. ( The Epoch Times reached out to Pfizer for comment.
In the same report, EMA also wrote: “It is likely that the fragmented species will not result in expressed proteins, due to their expected poor stability and poor translational efficiency (see below). However, the lack of experimental data on the truncated RNA and expressed proteins do not permit a definitive conclusion and need further characterisation. The 2021 EMA report stated that there is a lack of data to draw a definitive conclusion. ( Was this decision based on those phony Western blots?The EMA granted Pfizer/BioNTech conditional marketing authorization on Dec. 12, 2020.In Part 2 of this series, we will continue to discuss the implications of this quality issue and the potential outcome of vaccine-related injuries. Please consult a trusted professional for personal medical advice, diagnoses, and treatment. Email us at HealthReporter@epochtimes.nyc
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